ClinoStar 2
The ClinoStar 2 by CelVivo is an advanced 3D cell culture incubator designed to cultivate spheroids and organoids under low-shear, in vivo-like conditions. Featuring six independently controlled bioreactors, remote monitoring via CelVivo Cloud, and optional hypoxia control, it enables precise, long-term tissue modeling for biomedical research.
Hypoxia Unit
The CelVivo Hypoxia Module for ClinoStar enables precise oxygen control from atmospheric levels down to 2%, replicating physiological conditions found in tissues like lungs, brain, and tumors. It ensures rapid oxygen level stabilization and maintains hypoxic environments during brief exposures, enhancing the accuracy and reproducibility of 3D cell culture experiments.
Clinoreactor
The ClinoReactor by CelVivo is an advanced 10 mL bioreactor designed for 3D cell culture, enabling spheroid and organoid growth under low-shear, in vivo-like conditions. It features a removable lid for petri-dish-style access, integrated humidification to prevent media evaporation, and top vents for CO₂ equilibrium, ensuring optimal cell development.
CelVivo Cloud
CelVivo Cloud is a browser-based platform that enables remote control and monitoring of ClinoStar bioreactors from any internet-enabled device. It allows users to adjust environmental conditions such as CO₂, O₂, and temperature, and to control the rotational speed and direction of each bioreactor axle. The platform provides real-time video streaming from six integrated cameras, facilitating live observation of cultures.
APPLICATIONS
LIVER
3D structures can be used to study many aspects of liver function, including development, disease modeling (including NASH or fibrosis), cancer, drug screening for efficacy, and toxicology.